Mannose binding lectin deficiency and COVID-19 rates of thrombosis and mortality: Partial protection by immunodeficiency

Objective: The purpose of this study is to determine the effects COVID-19 infection on individuals with mannose binding lectin deficiency. Methods: An electronic medical records search was conducted for MBL deficiency and positive tests from March 2020-August 2022. Individualized chart analysis statistical performed. Results: Thirty-three people in WVU medicine health system carry a diagnosis were diagnosed COVID-19. mean age cohort 41 years. Seven had severe enough symptoms lead an emergency department visit. One person hospitalized. deficient 7 times odds hospitalization ( p = .1506, OR 7.06 (CI 1.117-44.52)) compared general public. There zero mortality among population. None patients reported thrombosis or blood clots. Conclusion: This retrospective cross-sectional those known suggest lower risk fatalities thrombotic events cohort. however higher ratio public, although not statistically significant.